Anti-DAXX Antibody Monoclonal

Product Name

DAXX, Monoclonal Antibody

Host

Mouse

Specificity

Mouse anti Human DAXX antibody, clone DAXX-01 recognizes human Death domain-associated protein 6, also known as DAXX, ETS1-associated protein 1, EAP1 or Fas death domain-associated protein. DAXX is a 740 amino acid ~81 kDa nucleoplasmic protein. DAXX is a regulator of apoptosis implicated in Fas and TGF beta induced apoptosis. DAXX is predominantly a nuclear protein, where it as a repressor of EtsI and Pax3 transactivation. When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm.

Form/Format

Purified IgG - liquid

Concentration

IgG concentration 1.0 mg/ml (lot specific)

Perservative Stabilisers

0.09% Sodium Azide

Preparation

Purified IgG prepared by affinity chromatography on Protein A

Immunogen

Recombinant C-terminal DAXX protein (aa 558-740)

Buffer Solution

TRIS buffered saline

Target Species

Human

Clonality

Monoclonal

Preparation and Storage

Store at 4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.