Description

Anti HTLV I Mouse Monoclonal Clone 68/4.

Antibodies that detect TNFRSF14 (HVEM) can be used in several scientific applications, including Western Blot, ELISA, Flow Cytometry, Immunocytochemistry and Immunohistochemistry (Paraffin).

These antibodies target TNFRSF14 (HVEM) in Human, Mouse and Rat samples. Our TNFRSF14 (HVEM) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Armenian Hamster, Goat and Rat. These antibodies have been verified by Knockdown to confirm specificity to TNFRSF14 (HVEM).

Find the TNFRSF14 (HVEM) antibody that fits your needs. Choose from 1 of 40 TNFRSF14 (HVEM) antibodies, which have been validated in experiments with 14 publications and 46 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

TNFRSF14 is a member of the TNF-receptor superfamily. TNFRSF14 was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to TNFRSF14 has been shown to be part of the viral entry mechanism. The cytoplasmic region of TNFRSF14 was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.

Activation of the signal transduction pathway involving TNFRSF14 in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these TNFRSF14 variants have not been determined.

Synonyms

Atar; CD270; CD40-like protein; herpes virus entry mediator; herpes virus entry mediator A; Herpesvirus entry mediator A; HGNC:11912; HVEA; Hvem; LIGHTR; RP3-395M20.6; sCD2710.

TNF receptor superfamily member 14; Tnfrs14; TNFRSF14; TR2; tumo; Tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; UNQ329/PRO509